Research Publication

Cognitive Performance and Aging

Hadanny Amir , Daniel-Kotovsky Malka , Suzin Gil , Boussi-Gross Rahav , Catalogna Merav , Dagan Kobi , Hachmo Yafit , Abu Hamed Ramzia , Sasson Efrat , Fishlev Gregory1 , Lang Erez , Polak Nir , Doenyas Keren , Friedman Mony , Tal Sigal , Zemel Yonatan, Bechor Yair , Efrati Shai.
"Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial."
Aging. June 2020. Volume 12, Issue 13 pp 13740—13761.

Ronit Shapira , Amos Gdalyahu , Irit Gottfried, Efrat Sasson , Amir Hadanny, Shai Efrati , Pablo Blinder , Uri Ashery.
"Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients"
Aging. Sep 2021. Volume 13, Issue 17 pp 20935—20961.

Yafit Hachmo , Amir Hadanny , Ramzia Abu Hamed , Malka Daniel-Kotovsky , Merav Catalogna , Gregory Fishlev, Erez Lang , Nir Polak , Keren Doenyas , Mony Friedman , Yonatan Zemel , Yair Bechor , Shai Efrati.
"Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial"
Aging. Nov 2020. Volume 12, Issue 22 pp 22445—22456.

Yafit Hachmo , Amir Hadanny, Sonia Mendelovic , Pnina Hillman , Eyal Shapira , Geva Landau , Hadar Gattegno , Avi Zrachya , Malka Daniel-Kotovsky , Merav Catalogna, Gregory Fishlev, Erez Lang , Nir Polak , Keren Doenyas, Mony Friedman , Yonatan Zemel , Yair Bechor , Shai Efrati.
"The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial"
Aging. Nov 2021. Volume 13, Issue 22 pp 24500—24510.

Hadanny, A., M. Rittblat, M. Bitterman, I. May-Raz, G. Suzin, R. Boussi-Gross, Y. Zemel, M. Catalogna, and S. Efrati.
“Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients–a retrospective analysis.”
Restorative Neurology and NeurosciencePreprint (2020): 1-15.

Shapira, R., B. Solomon, S. Efrati, D. Frenkel, and U. Ashery.
"Hyperbaric Oxygen Therapy Ameliorates Pathophysiology of 3xtg-Ad Mouse Model by Attenuating Neuroinflammation."
Neurobiol Aging62 (Feb 2018): 105-19.

Shapira, R., S. Efrati, and U. Ashery.
"Hyperbaric Oxygen Therapy as a New Treatment Approach for Alzheimer's Disease."
Neural Regen Res13, no. 5 (May 2018): 817-18.

Amir Hadanny, Relly Forer, Dina Volodarsky , Malka Daniel-Kotovsky , Merav Catalogna , Yonatan Zemel , Yair Bechor, Shai Efrati.
"Hyperbaric oxygen therapy induces transcriptome changes in elderly: a prospective trial"
Aging. Nov 2021. Volume 13, Issue 22 pp 24511—24523.

Hadanny Amir and Efrati Shai.
"The Hyperoxic-Hypoxic Paradox"
Biomolecules. June 2020. 10(6), 958.

Vadas, D., L. Kalichman, A. Hadanny, and S. Efrati.
"Hyperbaric Oxygen Environment Can Enhance Brain Activity and Multitasking Performance."
Front Integr Neurosci 11 (2017): 25.

Post Stroke Patients

Efrati, S., G. Fishlev, Y. Bechor, O. Volkov, J. Bergan, K. Kliakhandler, I. Kamiager, N. Gal, M. Friedman, E. Ben-Jacob, and H. Golan.
"Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients--Randomized, Prospective Trial."
PLoS One 8, no. 1 (2013): e53716.

Boussi-Gross, R., H. Golan, O. Volkov, Y. Bechor, D. Hoofien, M. S. Beeri, E. Ben-Jacob, and S. Efrati.
"Improvement of Memory Impairments in Poststroke Patients by Hyperbaric Oxygen Therapy."
Neuropsychology 29, no. 4 (Jul 2015): 610-21.

Chronic Pain Syndrome - Fibromyalgia

Efrati, S., H. Golan, Y. Bechor, Y. Faran, S. Daphna-Tekoah, G. Sekler, G. Fishlev, J. N. Ablin, J. Bergan, O. Volkov, M. Friedman, E. Ben-Jacob, and D. Buskila.
"Hyperbaric Oxygen Therapy Can Diminish Fibromyalgia Syndrome--Prospective Clinical Trial."
PLoS One 10, no. 5 (2015): e0127012.

Hadanny, A., Y. Bechor, M. Catalogna, S. Daphna-Tekoah, T. Sigal, M. Cohenpour, R. Lev-Wiesel, and S. Efrati.
"Hyperbaric Oxygen Therapy Can Induce Neuroplasticity and Significant Clinical Improvement in Patients Suffering from Fibromyalgia with a History of Childhood Sexual Abuse-Randomized Controlled Trial."
Front Psychol 9 (2018): 2495.

Ablin, J. N., S. Efrati, and D. Buskila.
"Building up the Pressure on Chronic Pain."
Clin Exp Rheumatol 34, no. 2 Suppl 96 (Mar-Apr 2016): S3-5.

Efrati, S., A. Hadanny, S. Daphna-Tekoah, Y. Bechor, K. Tiberg, N. Pik, G. Suzin, and R. Lev-Wiesel.
"Recovery of Repressed Memories in Fibromyalgia Patients Treated with Hyperbaric Oxygen - Case Series Presentation and Suggested Bio-Psycho-Social Mechanism."
Front Psychol 9 (2018): 848.

Lev-Wiesel, R., Y. Bechor, S. Daphna-Tekoah, A. Hadanny, and S. Efrati.
"Brain and Mind Integration: Childhood Sexual Abuse Survivors Experiencing Hyperbaric Oxygen Treatment and Psychotherapy Concurrently."
Front Psychol 9 (2018): 2535.

Traumatic Brain Injury, Post Concussion syndrome and Anoxic Brain Damage

Boussi-Gross, R., H. Golan, G. Fishlev, Y. Bechor, O. Volkov, J. Bergan, M. Friedman, D. Hoofien, N. Shlamkovitch, E. Ben-Jacob, and S. Efrati.
"Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury - Randomized Prospective Trial."
PLoS One 8, no. 11 (2013): e79995.

Efrati, S. and E. Ben-Jacob.
"Reflections on the Neurotherapeutic Effects of Hyperbaric Oxygen."
Expert Rev Neurother 14, no. 3 (Mar 2014): 233-6.

Hadanny, A., S. Abbott, G. Suzin, Y. Bechor, and S. Efrati.
"Effect of Hyperbaric Oxygen Therapy on Chronic Neurocognitive Deficits of Post-Traumatic Brain Injury Patients: Retrospective Analysis."
BMJ Open 8, no. 9 (Sep 28 2018): e023387.

Hadanny, A. and S. Efrati.
"Treatment of Persistent Post-Concussion Syndrome Due to Mild Traumatic Brain Injury: Current Status and Future Directions."
Expert Rev Neurother 16, no. 8 (Aug 2016): 875-87.

Hadanny, A., H. Golan, G. Fishlev, Y. Bechor, O. Volkov, G. Suzin, E. Ben-Jacob, and S. Efrati.
"Hyperbaric Oxygen Can Induce Neuroplasticity and Improve Cognitive Functions of Patients Suffering from Anoxic Brain Damage."
Restor Neurol Neurosci 33, no. 4 (2015): 471-86.

Tal, S., A. Hadanny, N. Berkovitz, E. Sasson, E. Ben-Jacob, and S. Efrati.
"Hyperbaric Oxygen May Induce Angiogenesis in Patients Suffering from Prolonged Post-Concussion Syndrome Due to Traumatic Brain Injury."
Restor Neurol Neurosci 33, no. 6 (2015): 943-51.

Tal, S., A. Hadanny, E. Sasson, G. Suzin, and S. Efrati.
"Hyperbaric Oxygen Therapy Can Induce Angiogenesis and Regeneration of Nerve Fibers in Traumatic Brain Injury Patients."
Front Hum Neurosci 11 (2017): 508.

Myocardial Dysfunction

Leitman, M., S. Efrati, S. Fuchs, A. Hadanny, Z. and Vered.
“The effect of hyperbaric oxygenation therapy on myocardial function.” 
The International Journal of Cardiovascular Imaging (Jan 2020).

Erectile Dysfunction

Hadanny, A., E. Lang, L. Copel, O. Meir, Y. Bechor, G. Fishlev, J. Bergan, M. Friedman, A. Zisman, and S. Efrati.
"Hyperbaric Oxygen Can Induce Angiogenesis and Recover Erectile Function."
Int J Impot Res 30, no. 6 (Nov 2018): 292-99.

Safety of Hyperbaric Oxygen Treatment

Hadanny, A., O. Meir, Y. Bechor, G. Fishlev, J. Bergan, and S. Efrati.
"The Safety of Hyperbaric Oxygen Treatment--Retrospective Analysis in 2,334 Patients."
Undersea Hyperb Med 43, no. 2 (Mar-Apr 2016): 113-22.

Hadanny, A., O. Meir, Y. Bechor, G. Fishlev, J. Bergan, and S. Efrati.
"Seizures During Hyperbaric Oxygen Therapy: Retrospective Analysis of 62,614 Treatment Sessions."
Undersea Hyperb Med 43, no. 1 (Jan-Feb 2016): 21-8.